Immune-Adherence Test for Syphilis: Comparison with TPI and VDRL Slide Tests

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Comparison of the VDRL slide, TPI, and FTA-ABS tests in experimental syphilis in rabbits.

The first serological test for syphilis, developed by Wassermann, Neisser, and Bruck (1906), was a complement-fixation test for reagin activity. Many tests for reagin activity have been developed since then, including the Kline, Kahn, Hinton, Kolmer, Mazzini, and VDRL slide tests. However, none of these is absolutely specific for syphilis. The VDRL slide test (Harris, Rosenberg, and Riedel, 194...

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Treponema pallidum haemagglutination test for syphilis. Comparison with TPI and FTA-ABS tests.

The Treponema pallidum haemagglutination (TPHA) test, the latest to be developed in the group of specific tests for syphilis, has been described by Tomizawa and Kasamatsu (1966), Rathlev (1967), Tomizawa, Kasamatsu, and Yamaya (1969), and Tringali (1970.) An automated microhaemagglutination technique, the AMHA-Tp test, has been evaluated by Cox, Logan, and Norins (1969) and Logan and Cox (1970)...

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VDRL slide flocculation reaction for syphilis performed on active sera.

The discovery of cardiolipin (Pangborn, 1941a) as the active agent in antigens for sero-reactions for syphilis enabled the production of chemically defined antigens, composed of cardiolipin, purified lecithin (Pangborn, 1941b), and cholesterol. Among the many tube and slide flocculation reactions based on the use of cardiolipin antigens, the Venereal Disease Research Laboratory (VDRL) slide flo...

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TPI test in treated syphilis.

The Treponema pallidum immobilization (TPI) test has received wide attention as a diagnostic test for syphilis, but few studies have appeared on the response of this test to adequate treatment for syphilis. The Blue Star study of the Public Health Service (Bauer, 1951 ; Shafer, Usilton, and Price, 1954) offered a group of patients who had had bonafide syphilis, who had been adequately treated, ...

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Treponema pallidum immune adherence test for serodiagnosis of syphilis. 2: Comparison with glass plate, TPHA, and FTA-ABS tests.

Using sera from 340 patients with syphilis the Treponema pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum haemagglutination (TPHA), and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA test agreed with those of the glass plate, TPHA, and FTA-ABS tests in 65%, 82%, and 73% of cases respectively. In the quantitative TPIA test no...

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ژورنال

عنوان ژورنال: Public Health Reports (1896-1970)

سال: 1954

ISSN: 0094-6214

DOI: 10.2307/4588817